ABSTRACT
This study was aimed to explore the impact of activated carbon adsorption modified by different concentrations of nitric acid and ammonia,in order to examine the impact on adsorption of mannotriose by modified activated carbon.The activated carbon was processed by different concentrations of nitric acid and ammonia.And then,the adsorption capacity of benzene,iodine,methylene blue and the purification effects on mannotriose were measured.The results showed that the active carbon modified by nitric acid and ammonia had some changes of adsorptions for methylene blue,iodine and benzene.The purification effect of mannotriose with nitric acid-modified activated carbon was declined.The purification effect of mannotriose with ammonia-modified activated carbon was increased.It was concluded that the pore structure of activated carbon had been changed by nitric acid and ammonia.The adsorption capacity of nitric acid modified active carbon to mannotriose was declined.However,the adsorption capacity of ammonia modified active carbon to mannotriose was increased.It showed that ammonia modified active carbon was suitable for the purification of mannotriose.And the adsorption capacity of iodine reflected the adsorption capacity of mannotriose by active carbon.
ABSTRACT
This article was aimed to determine the feasibility of neutral borosilicate glass ampoule as the inner packing material of Ginkgolides meglumine injection by studying the drug compatibility between Ginkgolides me-glumine injection and neutral borosilicate glass ampoule. On the basis of the Pharmaceutical Packaging Materials and Drug Compatibility Test Guidance Rules, the study was carried on the compatibility between Ginkgolides me-glumine injection and neutral borosilicate glass ampoule for packaging materials. The results showed that no mi-gration or adsorption quality of change between the Ginkgolides meglumine injection and neutral borosilicate glass ampoule. It had good compatibility between neutral borosilicate glass ampoule and Ginkgolides meglumine injec-tion. It was concluded that neutral borosilicate glass can be used as the packing materials of Ginkgolides meglumine injection.